Drug Interactions 9/6/2007

Drug Interactions

Drug interactions report for the following 10 medications:

include the following in the drug interactions report:
• Food

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• Drug-Drug interactions • Drug-Food interactions • Therapeutic Duplication

The following drug-drug interactions are found:

The risk of side effects from Atorvastatin may increase if you take Diltiazem. Although an interaction is possible, these drugs may be used together with caution. Contact your prescriber immediately if you experience unexplained muscle aches, muscle pain or tenderness, general weakness or fatigue, side or back pain, or decreased urination while taking Atorvastatin. (Last revised: 9/25/2001 1:00:00 PM)

Side effects from Beta-blockers (examples: Coreg®, Metoprolol or Lopressor® or Toprol®, Nadolol or Corgard®, Propranolol or Inderal®) may get worse if you take Diltiazem. Although an interaction is possible, these drugs are often used together for their beneficial effects. If your heart rate or blood pressure drops too low while taking these drugs, you may become dizzy or feel faint; do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away or if you notice new or increased swelling of your legs or ankles. Contact your prescriber immediately if you experience chest pain, difficulty breathing or shortness of breath, fainting spells, or slow heart rate (example: less than 60 beats per minute). (Last revised: 3/31/2005 9:30:00 AM)

Although an interaction is possible, these drugs may be used together. Antihypertensive Agents are drugs used to treat high blood pressure. If the blood pressure drops too low while taking these medications, you may become dizzy or feel faint. To limit this interaction, do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away. (Last revised: 8/29/2001 12:48:00 PM)

Atenolol ( Tenormin®) and Furosemide ( Delone™ | Furosemide | Lasix®)
Severity: Moderate

Atenolol ( Tenormin®) and Glyburide ( Diabeta® | Glycron™ | Glynase® PresTab® | Micronase®)
Severity: Moderate

Beta-blockers such as Atenolol may interfere with the actions of Antidiabetic Agents (examples: insulin, glyburide, Amaryl®, Avandia®, Glucophage®, Glucotrol®, Glucovance®). Beta-blockers can hide the symptoms of low blood sugar. Beta-blockers can also increase the blood sugar. Your health care provider may decide that taking these drugs together may benefit you. If you use a blood sugar monitoring device at home, check your blood sugar regularly. You should also learn how to recognize the signs of low blood sugar. (Last revised: 9/6/2001 5:11:00 PM)

Beta-blockers (examples: Coreg®, Metoprolol or Lopressor® or Toprol®, Nadolol or Corgard®, Propranolol or Inderal®) may interfere with the actions of Glyburide. Beta-blockers can hide the symptoms of low blood sugar. Beta-blockers can also increase the blood sugar. Your health care provider may decide that taking these drugs together may benefit you. If you use a blood sugar monitoring device at home, check your blood sugar regularly. You should also learn how to recognize the signs of low blood sugar. (Last revised: 9/6/2001 5:25:00 PM)

Atenolol ( Tenormin®) and Insulin Aspart ( NovoLog® | NovoLog® Flexpen™ | NovoLog® PenFill®)
Severity: Moderate

Beta-blockers (examples: Coreg®, Metoprolol or Lopressor® or Toprol®, Nadolol or Corgard®, Propranolol or Inderal®) may interfere with the actions of Insulin. Beta-blockers can hide the symptoms of low blood sugar. Beta-blockers can also increase the blood sugar. Your health care provider may decide that taking these drugs together may benefit you. If you use a blood sugar monitoring device at home, check your blood sugar regularly. You should also learn how to recognize the signs of low blood sugar. (Last revised: 1/20/2005 7:34:00 AM)

Atenolol ( Tenormin®) and Valsartan ( Diovan®)
Severity: Moderate

Although an interaction is possible, these drugs can be used together. Diltiazem may decrease the effectiveness of Doxercalciferol. Report any change in your response to the Doxercalciferol treatment to your prescriber. (Last revised: 7/11/2005 4:18:00 PM)

Taking Furosemide and Corticosteroids (examples: Aristocort®, Cortone®, Cortef®, Decadron®, Deltasone®, Hydrocortone®, Florinef®, Medrol®) together may lower the level of potassium in your blood. When the potassium in the blood is too low, this can cause muscle cramps, weakness, or an abnormal heart rhythm. Your health care provider may monitor your potassium level. A potassium supplement may be prescribed for patients with a low potassium level. (Last revised: 9/10/2001 4:14:00 PM)

Using these drugs together may lower the level of potassium in your blood. When the potassium in the blood is too low, this can cause muscle cramps, weakness, or an abnormal heart rhythm. Your health care provider may monitor your potassium level. A potassium supplement may be prescribed for patients with a low potassium level. (Last revised: 12/28/2001 11:23:00 AM)

Furosemide ( Delone™ | Furosemide | Lasix®) and Valsartan ( Diovan®)
Severity: Moderate

Antidiabetic Agents (examples: insulin, Actos®, Avandia®, Glucophage®, Glyset®, Precose®) may increase the actions of Glyburide to lower the blood sugar. Although an interaction is possible, these drugs are sometimes used together to help lower the blood sugar. If you use a blood sugar monitoring device at home, check your blood sugar regularly. You should also learn how to recognize the signs of low blood sugar. (Last revised: 9/7/2001 9:46:00 AM)

Insulin may increase the actions of Antidiabetic Agents (examples: insulin, Actos®, Avandia®, Glucophage®, Glyset®, Precose®) to lower the blood sugar. Although an interaction is possible, these drugs are often used together to help lower the blood sugar. If you use a blood sugar monitoring device at home, check your blood sugar regularly. You should also learn how to recognize the signs of low blood sugar. (Last revised: 1/19/2005 4:51:00 PM)

Corticosteroids (examples: Decadron®, Deltasone®, Medrol®, or Aristocort®) may decrease the actions of Antidiabetic Agents (Insulin or other medicines used to treat Diabetes), and increase the blood sugar. Although an interaction is possible, these drugs may be used together. If you use a blood sugar monitoring device at home, check your blood sugar regularly while taking these medicines together. (Last revised: 9/10/2001 4:21:00 PM)

Prednisone may decrease the actions of Antidiabetic Agents (medicines used for Diabetes), and increase the blood sugar. Although an interaction is possible, these drugs may be used together. If you use a blood sugar monitoring device at home, check your blood sugar regularly while taking these medicines together. (Last revised: 10/17/2001 2:56:00 PM)

Corticosteroids (examples: Aristocort®, Cortone®, Cortef®, Decadron®, Deltasone®, Hydrocortone®, Florinef®, Medrol®) may decrease the actions Insulin by increasing the blood sugar. Although an interaction is possible, these drugs may be used together. If you use a blood sugar monitoring device at home, check your blood sugar regularly while taking these medicines together. (Last revised: 1/20/2005 9:45:00 AM)

Cyclophosphamide ( Cytoxan® | Neosar®) and Prednisone ( Deltasone® | Predone™ | Sterapred® | Sterapred® DS)
Severity: Low

Cyclophosphamide and Immunosuppressives (medicines that decrease the response of the immune system) are commonly used together. While therapy is often designed to take advantage of the drugs' benefits, some interactions may occur; your practitioner will closely monitor the timing of your drug therapies and the outcomes of your treatment in order to get the best effect and limit the risk of side effects. Side effects can include an increased risk of infection or immunosuppression. If you get a fever, sore throat or other possible signs of an infection while receiving treatment, do not treat yourself. Seek health care professional evaluation and advice. (Last revised: 4/21/2005 9:38:00 AM)

Although an interaction is possible, these drugs are often used together. Additive benefits may occur when Corticosteroids (examples: Dexamethasone, Methylprednisolone, Prednisone, or Prednisolone) and Antineoplastic Agents (chemotherapy, medicine used to treat cancer and other conditions) are used together. The combined therapies are often designed to take advantage of these benefits. However, some side effects may include an increased risk of infection. If you notice signs or symptoms of an infection, such as a fever, sore throat, etc., do not treat yourself and seek your prescriber's evaluation and advice. (Last revised: 3/31/2005 2:45:00 PM)

Doxercalciferol ( Hectorol | Hectorol®) and Prednisone ( Deltasone® | Predone™ | Sterapred® | Sterapred® DS)
Severity: Low

Although an interaction is possible, these drugs are often used together. Regularly follow up with your health care provider to monitor your condition. An interaction is less likely with topical forms of Corticosteroids. (Last revised: 11/10/2004 12:30:00 PM)

Although an interaction is possible, these drugs are often used together. Regularly follow up with your health care provider to monitor your condition. (Last revised: 10/20/2004 4:52:00 PM)

Diuretics (water pills such as Bumex®, Demadex®, Diuril®, Hydrochlorothiazide, Dyazide®, Hygroton®, Lasix®, Lozol®, Maxide®) may decrease the actions of Antidiabetic Agents (medicines used to treat Diabetes) by increasing blood sugar. Although an interaction is possible, these drugs are often used together. If you use a blood sugar monitoring device at home, check your blood sugar regularly while taking these medicines together. (Last revised: 3/9/2006 6:45:00 PM)

Loop Diuretics (water pills such as Bumex®, Demadex®, or Lasix®) may decrease the actions of Glyburide by increasing blood sugar. Although an interaction is possible, these drugs are often used together. If you use a blood sugar monitoring device at home, check your blood sugar regularly while taking these medicines together. (Last revised: 3/9/2006 12:43:00 PM)

Furosemide ( Delone™ | Furosemide | Lasix®) and Insulin Aspart ( NovoLog® | NovoLog® Flexpen™ | NovoLog® PenFill®)
Severity: Low

Diuretics (water pills such as Bumex®, Demadex®, or Lasix®) may decrease the actions of Insulin by increasing blood sugar. Although an interaction is possible, these drugs are often used together. If you use a blood sugar monitoring device at home, check your blood sugar regularly while taking these medicines together. (Last revised: 3/22/2006 8:32:00 PM)

The following drug-food interactions are found:

Atorvastatin ( Lipitor®) and food interactions
Severity: High

Side effects from Atorvastatin may get worse if you drink grapefruit juice. Do not take Atorvastatin with grapefruit juice. Discuss with your health care provider why Atorvastatin and grapefruit juice should not be taken together. Orange juice is safe to drink with Atorvastatin. Contact your prescriber immediately if you experience unexplained muscle aches, muscle pain or tenderness, general weakness or fatigue, side or back pain, or decreased urination while taking Atorvastatin. (Last revised: 10/8/2002 1:01:00 PM)

Atenolol ( Tenormin®) and food interactions
Severity: Moderate

Atenolol may be taken without regard to most food or meals. There is one small study that suggests taking atenolol with orange juice directly might moderately lower atenolol's effectiveness. More data are needed to confirm these results. Why this interaction might occur is not known at this time. Until more data are available, it may be advisable to not significantly alter your orange juice intake while taking atenolol. (Last revised: 5/11/2006 1:53:00 PM)

Although less likely than with some other Calcium-Channel Blockers, Grapefruit juice and grapefruit-containing foods may increase the side effects of Diltiazem. Do not significantly increase grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. If your heart rate or blood pressure drops too low while taking this medicine, you may become dizzy or feel faint; do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away while taking this medicine. If you notice new or increased swelling of your legs or ankles, tell your health care provider. (Last revised: 10/7/2002 12:01:00 AM)

Therapeutic duplication found.

Atenolol, Diltiazem are Antianginals.
Atenolol, Diltiazem are Antiarrhythmics.
Glyburide, Insulin Aspart are Antidiabetic Agents.
Atenolol, Diltiazem, Furosemide, Valsartan are Antihypertensive Agents.
Cyclophosphamide, Prednisone are Immunosuppressives.
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Disclaimer: Do not stop taking your prescription drugs without first talking to your health care professional. This program may not cover all possible drug interactions or all effects that may occur when taking drugs with similar side effects. For example, there is little information available on how herbs interact with drugs. Different individuals may respond to medication in different ways. You should always consult your health care professional if you have questions about the drug(s) you are taking.